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How To ACTUALLY Lose Weight

Escaping the trap of weight loss with science-backed tools when diet, exercise, and everything else is failing

Jason Tran
JT
Published by Jason Tran
Tue Jan 21 2025

Remember that feeling? The sweat stinging your eyes on the treadmill, the gnawing hunger you pushed down with another celery stick, the relentless calorie counting scribbled in your food journal. For weeks, maybe months, you were a picture of discipline, a paragon of healthy living…and the scale still barely budged. Or worse, it crept up. The reflection staring back at you in the mirror was a constant reminder of your “failure.” That frustration, that sinking feeling of disappointment despite all your effort? It’s not you. It’s the outdated, oversimplified “calories in, calories out” mantra that’s been setting you up to fail.

Let’s break down what I mean. The core idea behind “calories in, calories out” is undeniably true at its most basic level: you need to be in a calorie deficit to lose weight. But the problem is that real life is far more complex than a simple equation. The prevailing message is that if you burn more calories than you consume, regardless of where those calories come from or how your body processes them, you will lose weight. This assumes that all calories are created equal and that your metabolism is a static, predictable machine. It ignores the crucial roles hormones, gut health, stress levels, and even the types of food you eat play in the fat-loss puzzle. Don’t get me wrong, you aren’t going to lose weight if you consume excess calories but that doesn’t take into account the many nuances of metabolism. It treats your body like a bank account, where every calorie is a dollar, and the only thing that matters is the balance. But your body isn’t a bank; it’s a highly sophisticated biological system constantly adapting to its environment. To unpack why the calorie myth is holding you back and explore the strategies that actually lead to sustainable fat loss, we need to first understand how we got here.

Understanding How Your Body Really Stores Fat

The Insulin Connection

Insulin is a hormone secreted by your pancreas in response to elevated blood sugar levels, typically after eating carbohydrates. Its primary role is to usher glucose (sugar) from your bloodstream into your cells, where it can be used for energy or stored as glycogen in the liver and muscles. However, when your glycogen stores are full, and there’s still excess glucose in the bloodstream, insulin takes that excess glucose and converts it into triglycerides, which are then shuttled into your fat cells for storage. Think of insulin as the “fat storage hormone.” Consistently high levels of insulin, often driven by a diet high in processed carbohydrates and sugars, can promote chronic fat storage and make it incredibly difficult to tap into those fat reserves for energy. In this sense, eating foods high in processed sugar is like telling your body “store fat!”

Insulin

Fat Cell Number vs. Size: The Liposuction Myth Debunked

Many people believe that liposuction is a quick and easy fix for getting rid of excess fat. While liposuction can remove fat cells, it doesn’t address the underlying metabolic issues that led to fat storage in the first place. Here’s why: you’re born with a generally fixed number of fat cells. When you gain weight, those fat cells expand to store more triglycerides. When you lose weight, they shrink, but they don’t disappear. Liposuction removes fat cells from the treated area. However, the remaining fat cells in your body (including those in other areas) can still expand if you continue to consume excess calories and have high insulin levels. More importantly, studies have shown that after liposuction, the body often compensates by increasing fat storage in other areas of the body. Furthermore, there are health risks associated with liposuction, and it doesn’t improve metabolic health. Ultimately, sustainable fat loss isn’t about removing fat cells; it’s about shrinking them through dietary and lifestyle changes that optimize your metabolism and hormonal balance.

The Calorie Conundrum: Not All Calories Are Created Equal (Carbs vs. Fats vs. Protein)

We’ve established that it’s not just about the number of calories you eat, but what those calories do within your body. This brings us to a fundamental flaw in the traditional calorie-counting approach: the assumption that all calories are created equal. They are NOT. To understand why, let’s look at the origin of the calorie itself:

The Calorie: A Crude Measurement from the 19th Century

The calorie, as we know it in nutrition, is based on a 19th-century system of measuring energy. Scientists would literally burn food in a device called a bomb calorimeter and measure the amount of heat released. This heat, measured in calories, was then used to assign caloric values to different foods. The problem? This is a completely different process than what happens inside the human body. Burning food in a lab doesn’t account for the complex biochemical reactions, hormonal responses, and individual variations that occur when we digest and metabolize food. It’s a gross measurement of potential energy, not a precise indicator of how your body will actually use or store that energy.

The Thermic Effect of Food (TEF): Your Body’s Internal Furnace

The Thermic Effect of Food (TEF) is the energy your body expends to digest, absorb, and process the nutrients from the food you eat. Different macronutrients (protein, carbs, and fats) have significantly different TEFs.

Protein: The Metabolism Booster

Protein has a much higher TEF than carbs or fats. Roughly 20-30% of the calories from protein are burned during digestion. This means that if you eat 100 calories of protein, your body only effectively absorbs 70-80 calories after the digestive process. Why is protein so metabolically demanding? Because it requires more energy to break down the complex amino acid chains and rebuild them into the proteins your body needs. In comparison, carbs and fats have much lower TEFs, typically around 5-10%.

Hormonal Responses: Insulin and the Fat Storage Switch

Beyond TEF, different macronutrients trigger different hormonal responses, which profoundly impact fat storage. We already touched on this in the previous section: Carbohydrates, especially refined carbohydrates and sugars, cause a rapid spike in blood sugar, leading to a surge of insulin. As we know, insulin’s primary role is to shuttle glucose out of the bloodstream. However, when glucose levels are high, it leads to excess triglycerides, which leads to increased fat storage. In contrast, protein and fats have a much smaller impact on blood sugar and insulin levels. Fat causes the least amount of an insulin response. This means that prioritizing protein and healthy fats in your diet can help keep insulin levels stable, making it easier to access your stored fat for energy.

Ketosis: Tapping Into Your Body’s Fat-Burning Potential

Given what we now know about carbohydrates, insulin, and fat storage, it might seem logical to drastically reduce carb intake to force the body to burn fat. This is the core principle behind the ketogenic diet, and on paper, it makes a lot of sense.

Ketosis: Shifting Your Body’s Fuel Source

Ketosis is a metabolic state in which your body primarily burns fat for fuel instead of carbohydrates. When you drastically limit your carbohydrate intake (typically to around 20-50 grams per day), your body depletes its glycogen (stored glucose) reserves. In response, your liver starts producing ketones from fat. These ketones become the primary energy source for your brain, muscles, and other tissues. Essentially, you’re training your body to become a fat-burning machine.

Potential Benefits for Fat Loss

The ketogenic diet has shown promise in promoting fat loss for several reasons. First, it can lead to reduced appetite due to the satiating effects of fat and protein. The high satiety of keto-friendly foods (fats and proteins) often leads to natural calorie restriction. However, if you’re consuming excess calories on keto, even if they’re primarily from fat, you still won’t lose weight. Second, it can improve insulin sensitivity, making it easier for your body to regulate blood sugar levels. Third, it can increase fat oxidation, meaning your body becomes more efficient at burning fat for energy. Many people experience rapid weight loss in the initial stages of keto.

Focus on Whole, Unprocessed Foods (Regardless of Diet)

Whether you choose to follow a ketogenic diet or another dietary approach, the most important principle is to prioritize whole, unprocessed foods. Nutrient deficiencies can also be a concern if you’re not careful to consume a wide variety of nutrient-rich, keto-friendly foods. Focus on healthy fats (avocados, olive oil, nuts, seeds), lean protein sources (fish, chicken, tofu), and non-starchy vegetables (leafy greens, broccoli, cauliflower). Avoid processed foods, sugary drinks, and refined carbohydrates, regardless of whether they “fit” within the specific macros of your chosen diet. Sustainable fat loss is about nourishing your body with nutrient-dense foods, not simply manipulating macronutrient ratios.

Exploring the 36-Hour Fast: A Metabolic Reset Button?

Extended fasting, particularly the 36-hour fast, has gained popularity as a potentially powerful tool for fat loss and overall health. It’s a more extreme approach than daily intermittent fasting, and therefore, requires careful consideration.

A 36-hour fast involves abstaining from all food (but continuing to drink water, black coffee, or unsweetened tea) for a consecutive 36-hour period. For example, you might eat dinner on Monday evening and then not eat again until breakfast on Wednesday morning. It’s important to differentiate this from simple overnight fasting (e.g., 12-16 hours), as the effects become more pronounced beyond the 24-hour mark.

Timing Matters: The Strategic Calorie Deficit

The 36-hour fast is essentially a way to create a larger, but less frequent, calorie deficit. The goal is to strategically reduce your overall weekly calorie intake without feeling constantly deprived. By concentrating the calorie restriction into a single, longer period, you might find it easier to adhere to a lower average daily calorie intake than if you were constantly trying to restrict calories every day. The most effective part of the 36 hour fast is that you can still eat normal, reasonably sized meals on the other days of the week. It gives your body time to tap into fat stores that it normally wouldn’t use when given food in intermittent fasting windows.

Potential Benefits: More Than Just Calorie Restriction

The benefits of a 36-hour fast extend beyond simple calorie restriction. During the extended fasting period, several important physiological processes occur:

  • Reduced Insulin Resistance: Prolonged fasting can help improve insulin sensitivity. When you’re not constantly consuming food, your insulin levels stay lower, allowing your cells to become more responsive to insulin’s signals.
  • Autophagy: After about 24 hours of fasting, your body starts to ramp up autophagy, a cellular “housekeeping” process where damaged or dysfunctional cells are broken down and recycled. This can contribute to cellular repair and longevity.
  • Increased Growth Hormone: Fasting can trigger a significant increase in growth hormone, which plays a role in muscle preservation and fat burning.
  • Fat Storage Depletion: As your body depletes its glycogen stores, it begins to rely more heavily on burning fat for fuel, leading to a reduction in fat storage.

Important Considerations

While the 36-hour fast can offer potential benefits, it’s not without its risks and should be approached with caution. If you consistently rely on 36-hour fasts without ensuring adequate nutrient intake on your non-fasting days, you risk developing nutrient deficiencies. After a 36-hour fast, some individuals may experience strong cravings and a tendency to overeat, negating the calorie deficit created during the fast. It’s crucial to plan your re-feeding meal carefully and focus on nutrient-dense foods. If you’re considering a 36-hour fast, it’s essential to listen to your body, stay hydrated, and consult with a healthcare professional or registered dietitian to ensure it’s safe and appropriate for you. A gradual approach, starting with shorter fasting periods, is often recommended.

Ozempic and the “Easy” Way Out: The Hidden Costs of Appetite Suppression

In an era obsessed with quick fixes, medications like Ozempic have emerged as seemingly miraculous solutions for weight loss. While they offer significant potential, it’s crucial to understand how they work and the potential downsides before considering them.

How Ozempic Works: Appetite Suppression Through GLP-1

Ozempic is a medication that belongs to a class of drugs called GLP-1 receptor agonists. GLP-1 (glucagon-like peptide-1) is a naturally occurring hormone that plays a crucial role in regulating blood sugar and appetite. Ozempic mimics the effects of GLP-1, leading to several key actions. It reduces appetite by slowing down gastric emptying (the rate at which food leaves your stomach), making you feel fuller for longer. It also acts on the brain to reduce hunger signals. It stimulates insulin release from the pancreas when blood sugar levels are high, helping to lower blood sugar.

Significant Weight Loss Potential

Due to its powerful appetite-suppressing effects, Ozempic can lead to significant weight loss. Clinical trials have demonstrated that individuals taking Ozempic can lose an average of 15-20% of their body weight. This has made it an attractive option for those struggling with obesity or overweight conditions.

The Hidden Cost: Muscle Loss and Bone Density Concerns

While the weight loss numbers can be impressive, it’s crucial to consider what type of weight is being lost. A concerning aspect of Ozempic is that a significant portion of the weight loss can come from muscle mass and bone density, not just fat. Muscle mass is metabolically active tissue that helps burn calories, and bone density is critical for long-term skeletal health. Losing muscle mass can further slow down your metabolism, making it harder to maintain weight loss in the long run. Resistance training is essential to minimize muscle loss. Additionally, decreased bone density puts you at a higher risk for fractures and osteoporosis. Ozempic can cause a range of side effects, including nausea, vomiting, diarrhea, constipation, abdominal pain, and fatigue. In rare cases, it can also be associated with more serious side effects, such as pancreatitis and gallbladder problems.

Ozempic as a Tool, Not a Magic Bullet

It’s essential to view Ozempic as a tool that can potentially be helpful for people who are severely struggling with weight loss and its related health complications. It is most beneficial for individuals who cannot follow low calorie diets without extreme discomfort. However, it shouldn’t be considered a standalone solution or a “quick fix.” Long-term success requires a comprehensive approach that includes healthy eating habits, regular exercise (especially resistance training to preserve muscle mass), and lifestyle modifications. Before starting Ozempic, it’s essential to have a thorough discussion with your doctor about the potential risks and benefits, and to ensure you understand that it requires a commitment to healthy lifestyle changes to achieve sustainable results and minimize the potential for muscle loss and bone density reduction.

The Basal Metabolic Rate (BMR) Trap: Why Losing Weight Can Actually SLOW You Down

You’ve diligently cut calories, seen the scale drop, and felt a surge of initial success. But then, frustratingly, the weight loss plateaus, despite maintaining the same restrictive diet. You might even start gaining weight again. This isn’t just bad luck; it’s a consequence of the Basal Metabolic Rate (BMR) trap.

What is BMR? Your Body’s Idling Engine

Your Basal Metabolic Rate (BMR) is the number of calories your body burns at rest, just to keep basic functions running (breathing, circulation, cell maintenance, etc.). Think of it as your body’s “idling engine” – the energy it needs to function even if you’re lying in bed all day. A significant portion of your daily calorie expenditure comes from your BMR. Importantly, muscle mass is a major determinant of your BMR. Muscle tissue is metabolically active, meaning it burns more calories at rest than fat tissue. The more muscle you have, the higher your BMR, and the more calories you burn throughout the day.

The Calorie Deficit Dilemma: Lowering the Speed of the Engine

When you consistently restrict your calorie intake to create a deficit for weight loss, your body perceives a state of energy scarcity. In response, it tries to conserve energy by slowing down your BMR. It essentially lowers the speed of your “idling engine.” This means that you’re burning fewer calories at rest than you were before you started dieting, making it harder to continue losing weight with the same level of calorie restriction.

Sustained calorie restriction can create a vicious cycle. As you lose weight (especially if that weight loss includes muscle mass), your BMR decreases further. This makes it harder to maintain the calorie deficit needed for continued weight loss, and you may eventually plateau or even regain weight. The body is programmed to survive, and it will fight to maintain energy balance.

The “Biggest Loser” Reality Check

A sobering example of the BMR trap in action is the aftermath of the popular TV show “The Biggest Loser.” A study published in Obesity tracked contestants from the show six years after their dramatic weight loss. Shockingly, almost all of them had regained a significant portion of the weight they lost. More importantly, their metabolisms had slowed down dramatically, burning significantly fewer calories than expected for their size and body composition. This illustrates how extreme calorie restriction and weight loss can have long-term negative effects on metabolic rate.

Counteracting the BMR Reduction: Fueling the Fire

Resistance training is crucial for maintaining and building muscle mass. Building or preserving muscle helps to offset the decrease in BMR that typically occurs during weight loss. Aim for at least two to three strength-training sessions per week, focusing on compound exercises that work multiple muscle groups (squats, deadlifts, bench press, rows, overhead press).

Consuming enough protein is essential for muscle repair and growth. Aim for at least 0.8 grams of protein per pound of body weight, and consider increasing this further during periods of calorie restriction.

Instead of drastically slashing calories, aim for a more moderate and sustainable calorie deficit. This will minimize the impact on your BMR and make it easier to maintain weight loss in the long run. The deficit should be enough to cause fat loss without putting the body in starvation mode.

Incorporating strategic “refeed days” with slightly higher calorie and carbohydrate intake can help to temporarily boost your metabolism and prevent it from adapting too much to the calorie restriction.

Exercise: Overrated? The Inefficiency of Working Out For Fat Loss

We’re constantly told that exercise is essential for weight loss, and while it undeniably offers numerous health benefits, its role in purely fat loss is often overstated. It’s crucial to have realistic expectations about the impact of exercise and to understand why it might not be as effective as you think for burning off stubborn fat.

The Calorie Expenditure Illusion

Overestimating Burns and Underestimating Effort: One of the biggest pitfalls is overestimating the number of calories you burn during exercise and underestimating the sheer amount of exercise needed to create a significant calorie deficit. Fitness trackers and cardio machines often provide inflated calorie burn estimates. A typical 30-minute cardio session might burn only 200-300 calories (and sometimes even less, depending on intensity and individual factors). While every little bit helps, consider that a single slice of pizza can easily contain that many calories. The math simply doesn’t always add up. You would have to spend a significant amount of time doing cardio to burn a worthwhile amount of calories.

The Appetite Surge: Exercise-Induced Hunger

Intense exercise can trigger a surge in appetite, potentially negating the calorie deficit you worked so hard to achieve. After a grueling workout, your body releases hormones that stimulate hunger, and you might find yourself craving high-calorie foods to replenish your energy stores. If you’re not mindful of your food intake, you could easily consume more calories than you burned during the workout, leading to a net calorie surplus and preventing fat loss. It’s common to subconsciously reward yourself with food after exercise, undermining your efforts.

Resistance Training vs. Cardio: A Tale of Two Workouts

While cardio has its place, resistance training (weightlifting) is generally more beneficial for long-term fat loss due to its impact on muscle mass. As we’ve discussed, muscle tissue is metabolically active, meaning it burns more calories at rest than fat tissue. By building muscle through resistance training, you increase your BMR, making it easier to burn fat throughout the day, even when you’re not exercising. Cardio, on the other hand, primarily burns calories during the workout itself. While cardio burns calories, the process does not protect muscle mass nearly as much as resistance training, so more muscle will be burned along with the fat.

It’s important to remember that exercise offers a plethora of health benefits beyond weight loss, including improved cardiovascular health, stronger bones, reduced risk of chronic diseases, better mood, and increased energy levels. These benefits are invaluable, regardless of whether exercise is directly contributing to significant fat loss. Therefore, you should exercise because it’s good for your health, not just because you want to lose weight.

NEAT: The Fat Loss Secret Hiding in Plain Sight

What is NEAT? The Energy of Everyday Movement

Non-Exercise Activity Thermogenesis (NEAT) encompasses all the energy you expend during physical activities other than planned exercise, sleeping, eating, or sports-like exercise. It’s the energy you burn through everyday movements like fidgeting, walking around the house, standing while working, doing household chores, gardening, and even maintaining posture. Examples of NEAT include:

  • Fidgeting (tapping your feet, bouncing your leg)
  • Walking to the mailbox
  • Taking the stairs instead of the elevator
  • Standing while working at a desk
  • Doing housework (cleaning, laundry)
  • Gardening
  • Grocery shopping

The Significance of NEAT: A Bigger Impact Than You Think: NEAT can account for a surprisingly large portion of your daily energy expenditure. In some individuals, it can contribute to hundreds, even thousands, of calories burned each day. This is particularly true for people who have naturally high levels of NEAT (i.e., those who are naturally fidgety or active). While formal exercise might burn a few hundred calories, accumulating small increments of NEAT throughout the day can add up to significantly more.NEAT is largely unconscious, which means it doesn’t rely on willpower or motivation like exercise does. Once you establish habits that promote more movement throughout the day, you’ll burn more calories almost automatically. It’s important to note that the body is remarkably adaptable. While increasing NEAT can boost your energy expenditure, your body might compensate by decreasing other metabolic processes. The body attempts to retain homeostasis, so it will attempt to match the energy expenditure. This compensation might not fully negate the benefits of increased NEAT, but it’s something to be aware of. Therefore, it is not the end-all-be-all.

Practical Tips to Boost Your NEAT Throughout the Day

The beauty of NEAT is that it doesn’t require intense effort or a structured workout plan. Small, consistent changes to your daily routine can make a big difference:

  • Take the Stairs: Opt for the stairs instead of the elevator whenever possible.
  • Walk During Phone Calls: Pace around your office or house while you’re on the phone.
  • Use a Standing Desk: Invest in a standing desk or a desk converter to alternate between sitting and standing throughout the day.
  • Park Further Away: Park your car further away from your destination and walk the extra distance.
  • Set Reminders to Move: Use a phone app or fitness tracker to remind you to stand up and move around every 30 minutes.
  • Fidget Consciously: Even seemingly insignificant movements like tapping your fingers or bouncing your leg can burn extra calories.
  • Household Chores: Doing household chores is a great way to incorporate movement into your daily routine.

The Sustainable Fat Loss Strategy: Long-Term Success is About More Than Just Diet and Exercise

If you’ve been stuck in the frustrating cycle of calorie counting, endless cardio, and minimal results, we hope this post has shed light on the underlying reasons why. As you’ve discovered, the conventional “calories in, calories out” approach is a gross oversimplification of the complex processes governing fat loss. It fails to account for the roles of hormones (like insulin), the quality of your food, your Basal Metabolic Rate (BMR), the impact of exercise on appetite, and the power of unconscious movements (NEAT).

Remember that sustainable fat loss is a marathon, not a sprint. It’s about creating lasting lifestyle changes that nourish your body, optimize your metabolism, and promote long-term health. It is about utilizing various tools like resistance training, a good diet and non exercise activity to promote fat loss.

If you’re interested in diving deeper into some of the specific topics we covered, be sure to check out our other articles on the ketogenic diet and effective weight training strategies. Knowledge is power, and by continuing to educate yourself, you’ll be better equipped to break free from the fat loss trap and achieve the results you deserve!

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